Penicillin therapy in icteric leptospirosis
Am J trop med hyg
; 39(4): 388-90, 1988. tab
Article
em En
| MedCarib
| ID: med-15021
Biblioteca responsável:
BB9.1
Localização: BB9.1 / JM3.1; RC960.A42
ABSTRACT
A prospective, controlled randomized study of penicillin therapy in icteric human leptospirosis was carried out between 1 October 1983 and 31 December 1986. Thirty-eight patients received intravenous crystalline penicillin for 5 days, while 41 assigned tests made on the day of admission revealed no significant differences between the 2 groups. There was no significant difference in time for defervescence, return of biochemical parameters to normal, incidence of iritis, or mortality in the 2 groups. Three patients (7.3 percent) in the control group and 1 patient (2.6 percent) in the treatment group died. The overall mortality rate was 5.9 percent. Leptospira were recovered from urine cultures in 6 control patients but from none of the treated patients' post-treatment cultures. We conclude that penicillin has little effect on clinical outcome in icteric leptospirosis (AU)
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Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Penicilinas
/
Leptospirose
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
País/Região como assunto:
Barbados
/
Caribe ingles
Idioma:
En
Revista:
Am J trop med hyg
Ano de publicação:
1988
Tipo de documento:
Article