Treatment of sickle cell disease in early childhood in Jamaica
Am J Pediatr Hematol Oncol
; 7(3): 235-9, 1985.
Artigo
em Inglês
| MedCarib
| ID: med-15907
Biblioteca responsável:
JM3.1
Localização: JM3.1; Reprint Collection
ABSTRACT
The Jamaican sickle cell cohort study, based on neonatal diagnosis of all cases of sickle cell disease among 100 000 consecutive births, has identified acute splenic sequestration (ASS) and pneumoccocal disease as the most important complications in early life. The etiology of ASS is unknown and prophylaxis is therefore not possible. For first attacks, attention has been directed to parental education to achieve earlier diagnosis. Recurrent attacks may be prevented by prophylactic splenectomy. A controlled trial on the prevention of pneumococcal disease has indicated many pneumococcal septicemias in children given the 14 valent pneumococcal vaccine between the ages of 6 months and 3 years. No pneumococcal isolations occurred during the same period in children given monthly long-acting prophylactic penicillin. A controlled trial of foliate supplementation for 1 year in children aged 6 months to 4 years indicated no difference between control and treatment groups in hemoglobin levels or weight and height velocity. The MVC was 4 fl less in the supplemented group. A controlled trial of feeder vessel photocoagulation in the therapy of proliferative retionpathy indicated significantly less vitreous hemorrhage in treated patients but choroidal neovascularization was a common complication of xenon arc therapy and retinal tears commonly followed the use of Argon laser. A new trial of scatter therapy is in progress. (AU)
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
/
ODS3 - Meta 3.2 Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
Problema de saúde:
Meta 3.2: Reduzir as mortes de recém nascidos e crianças com menos de 5 anos
/
Zoonoses
/
Meningite
/
Obesidade
/
Outras Doenças Sanguíneas
/
Doenças de Células Falciformes
/
Cuidados de Saúde Neonatal
/
Doenças Não Transmissíveis
/
Nutrição
Base de dados:
MedCarib
Assunto principal:
Infecções Pneumocócicas
/
Esplenopatias
/
Anemia Falciforme
Tipo de estudo:
Ensaio clínico controlado
/
Estudo observacional
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Criança
/
Criança, pré-escolar
/
Humanos
/
Lactente
País/Região como assunto:
Caribe Inglês
/
Jamaica
Idioma:
Inglês
Revista:
Am J Pediatr Hematol Oncol
Ano de publicação:
1985
Tipo de documento:
Artigo