Metformin: an important tool for endocrinology in the West Indies. New tricks for an old drug
The british journal of diabetes and vascular disease
; 9(5): 232-236, Sep. 2009. ilus
Artigo
em Inglês
| MedCarib
| ID: med-17691
Biblioteca responsável:
TT5
ABSTRACT
Against the backdrop of an obesity pandemic, comes an increasing prevalence of metabolic (e.g. type 2 diabetes mellitus) and reproductive abnormalities (e.g. polycystic ovarian syndrome) mediated by the phenomenon of insulin resistance. Metformin is an inexpensive and widely available drug which partly through an insulin sensitising action has an antidiabetic action with unique cardioprotective effects and which has value in preventing progression of pre-diabetes to diabetes. Despite mounting favourable data its role in polycystic ovarian syndrome remains unsettled. The recent finding for its safety and efficacy in gestational diabetes, however, will no doubt lift concerns over its use in women in the reproductive age group. One immediate result would be its earlier and greater therapeutic application in under-resourced environments where cost and emotional barriers to insulin exist.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Síndrome do Ovário Policístico
/
Trinidad e Tobago
/
Resistência à Insulina
/
Diabetes Mellitus
/
Obesidade
Tipo de estudo:
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Recém-Nascido
/
Gravidez
País/Região como assunto:
Caribe
/
Caribe Inglês
/
Trinidad e Tobago
Idioma:
Inglês
Revista:
The british journal of diabetes and vascular disease
Ano de publicação:
2009
Tipo de documento:
Artigo
Instituição/País de afiliação:
The University of the West Indies/Trinidad and Tobago