Metformin: an important tool for endocrinology in the West Indies. New tricks for an old drug
The british journal of diabetes and vascular disease
; 9(5): 232-236, Sep. 2009. ilus
Article
em En
| MedCarib
| ID: med-17691
Biblioteca responsável:
TT5
ABSTRACT
Against the backdrop of an obesity pandemic, comes an increasing prevalence of metabolic (e.g. type 2 diabetes mellitus) and reproductive abnormalities (e.g. polycystic ovarian syndrome) mediated by the phenomenon of insulin resistance. Metformin is an inexpensive and widely available drug which partly through an insulin sensitising action has an antidiabetic action with unique cardioprotective effects and which has value in preventing progression of pre-diabetes to diabetes. Despite mounting favourable data its role in polycystic ovarian syndrome remains unsettled. The recent finding for its safety and efficacy in gestational diabetes, however, will no doubt lift concerns over its use in women in the reproductive age group. One immediate result would be its earlier and greater therapeutic application in under-resourced environments where cost and emotional barriers to insulin exist.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Síndrome do Ovário Policístico
/
Trinidad e Tobago
/
Resistência à Insulina
/
Diabetes Mellitus
/
Obesidade
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
País/Região como assunto:
Caribe
/
Caribe ingles
/
Trinidad y tobago
Idioma:
En
Revista:
The british journal of diabetes and vascular disease
Ano de publicação:
2009
Tipo de documento:
Article