Systolic left ventricular dysfunction detected by echocardiography: demographics and aetiology - abstract

ABSTRACT

The aim of this retrospective study was to determine the demographic features and causes of heart failure in patients presenting a tertiary care institution 65 patients aged >16 years with an ejection fraction (EF) < 40 percent, undergoing echocardiography during a two-year period, 1992-94, were included in the study. The mean age was 60 ñ 12 years, 68 percent were male, 50 percent and 42 percent were African and East Indian, respectively. The prevalence of diabetes and hypertension was 40 percent and 45.3 percent respectively. The majority of patients were in NYHA class II or III. The mean left ventricular ejection fraction (LVEF) was 29.7 ñ 8.6 percent. There was no correlation between NYHA class and LVEF at initial presentation. The underlying causes of heart failure were coronary artery disease (CAD) (42 percent), idiopathic dilated cardiomyopathy (10.9 percent), hypertensive heart disease (9.4 percent), alcohol related dilated cardiomyopathy (7.8 percent), valvular heart disease (7.8 percent), myocarditis (1.6 percent) and hypertrophic cardiomyopathy (1.6 percent). The dominant primary cause could not be determined in 18.8 percent. LVEF was similarly depressed in the two major ethnic groups and in the ischaemic and non-ischemic cardiomyopathy groups. We concluded that CAD was the most common cause of LV systolic dsyfunction and that LVEF was not related to ethnicity, aetiology or severity of symptoms. (AU)