Treatment effects in trichuris dysentery syndrome
Acta Paediatr
; 83: 1182-7, 1994.
Artigo
em Inglês
| MedCarib
| ID: med-4785
Biblioteca responsável:
JM3.1
Localização: JM3.1; Reprint Collection
ABSTRACT
Heavy infection with geohelminth trichuris trichiura causes the Trichuris dysentery syndrome (TDS). Growth retardation and anaemia are charcteristic of TDS and both are associated with poor development. We have examined the growth and developmental responses to treatment in 19 children aged 27-84 months with TDS. Development levels (DQ) were measured with the Griffiths mental development scales. Compared with a control group matched for age, gender and neighbourhood, the TDS children initially had serious deficits in DQ (24 points, p < 0.001). After a year of anthelmintic treatment, the TDS children showed improvement in locomotor development (p<0.001) compared with the controls. The TDS children also had initial deficits in height-for-age, weight-for-height, mid upper arm circumference and haemoglobin levels. They caught up rapidly in indices of wasting (weight-for-height and mid-upper arm circumference) and showed steady improvement in height-for-age and haemoglobin levels. Catch-up in height was comparable to that of children recovering from coeliac disease. The importance of continuing prevention after initial treatment is highlighted (AU)
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Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Diarreia
/
Helmintíase
/
Doenças Negligenciadas
/
Zoonoses
Base de dados:
MedCarib
Assunto principal:
Tricuríase
/
Deficiências do Desenvolvimento
/
Disenteria
/
Mebendazol
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Acta Paediatr
Ano de publicação:
1994
Tipo de documento:
Artigo