Liver glutamic-aspartic transaminase activity in human diabetes

ABSTRACT

Liver glutamic-aspartic transaminase activity has been investigated in 19 diabetic subjects before and after treatment of the diabetic state. In 15 patients who were passing no sugar in the urine at the time of the second biopsy the mean level of transaminase activity was 0.146 ñ 0.013 units whereas before treatment the activity had been 0.0213 ñ 0.011 units. This difference is highly significant statistically. There was no apparent relation between the initial level of transaminase activity or the change in activity and the type or duration of the diabetes or of the treatment given (AU)