Seroepidemiology of chlamydial infection among a sexually-active population in Barbados

ABSTRACT

During a two-year period, sera from 1179 patients with urogenital tract symptoms and from 256 controls were tested for IgG and IgA antibodies to Chlamydia trachomatis, using a commercially prepared indirect immunoperoxidase assay. Of the patient sera, 1051 (89 percent) were from female patients and 128 (11 percent) were from males. Specimens were received from patients attending private practitioners (424), government polyclinics (348), the Queen Elizabeth Hospital (206), the Barbados Family Planning Association (117) and various other source (84). Nine hundred and fifty-nine of specimens (81 percent) from all patients had IgG titres of 64 or greater, and 441 (37 percent) had IgA titres of 16 or greater. A lower proportion of male patients (43 percent) than female patients (61 percent) had IgG titres of 128 or greater. Among 76 control females attending the antenatal clinic, IgG were detected in 76 percent and IgA in 16 percent, while among 75 adult blood donors, IgG was detected in 70 percent and IgA in 39 percent. A group comprising 97 asymptomatic children aged 9 months to 13 years, and 8 adolescents aged 14 - 18 years was also studied. IgG antibodies (titre