Intravaginal misoprostol versus dinoprostone as cervical ripening and labor-inducing agents

ABSTRACT

OBJECTIVE: To compare dinoprostrone (prostaglandin E2) and misoprostol (prostaglandin E1) for ripening the cervix and inducing labour at term. METHODS: Sixty-three women are randomized to receive 100 micrograms misoprostol or 3mg dinoprostone, both are intravaginal tablets. RESULTS: There was no statistical difference between the groups of pre-induction status. The mean Bishop scores before drug insertion were almost identical. Twelve hours after insertion, the mean score in the Bishop score was significantly higher in those receiving misoprostol (5.0 versus 3.3) (P= .008). However, there was no significant difference in induction-to-delivery interval, spontaneous labor rates, types of delivery, fetal outcome, or maternal complications. CONCLUSION: Misoprostol is as effective as dinoprostone for inducing labor at term. (AU)