A histochemical investigation of the concept of placental insufficiency

ABSTRACT

Using histochemical methods, the distribution and quantities of 10 enzymes were studied in 91 placentae representing normal and various types of abnormal pregnancies. It was concluded that the increasing concentration of alkaline phosphatase and glucose-6-phosphatase, and the decreasing concentration of acid phosphatase in the trophoblast are probably features of placental aging, and may also be associated with placental insufficiency (Summary)