A multiplicity of reactions to carbutamide (BZ-55) therapy

ABSTRACT

The case of a diabetic adult male who exhibited a number of serious toxic reactions to carbutamide administration is reported. The findings included thrombocytopenia, fever, lymphocytosis, generalized lymphadenopathy, exfoliative dermatitis, hepatitis and the development of a secondary anemia. Recovery followed administration of cortisone. Delayed "hypoglycemic" episodes were associated with adminstration of high dosage of the drug.(AU)