Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study
Rev Panam Salud Publica
; 43, dic. 2019
Artigo
em Inglês
| PAHO-IRIS
| ID: phr-51755
Biblioteca responsável:
US1.1
ABSTRACT
[ABSTRACT]. Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname. Methods. This was a retrospective cohort study using data from the national TB and HIV databases for 2010 – 2015. The survival probability of TB and TB/HIV co-infected patients was analyzed using the Kaplan-Meier estimates and the log-rank test. A Cox proportional hazard model was applied. Results. The study showed that HIV-seropositivity (aHR 2.08, 95%CI 1.48 – 2.92) and older age (aHR 5.84, 95%CI 3.00 – 11.4) are statistically associated with higher mortality. For the TB/HIV co-infected patients, TB treatment (aHR 0.43, 95%CI 0.35 – 0.53) reduces the risk of death. Similarly, HIV treatment started (aHR 0.15, 95%CI 0.12 – 0.19) and delayed (aHR 0.25, 95%CI 0.13 – 0.47) result in less hazard for mortality; Directly-Observed Treatment (aOR 0.16, 95%CI 0.09 – 0.29) further reduces the risk. Conclusions. The Ministry of Health of Suriname should develop strategies for early case-finding in key populations, such as for HIV and TB in men 60 years of age and older. Implementation of Isoniazid Preventive Therapy for HIV should be pursued. Scaling up TB and HIV treatment, preferably through supervision, are essential to reducing the TB/HIV mortality.
Texto completo:
Disponível
Coleções:
Bases de dados de organismos internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
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Doenças Negligenciadas
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Tuberculose
/
AIDS
/
Tuberculose
Base de dados:
PAHO-IRIS
Assunto principal:
Suriname
/
Tuberculose
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Mortalidade
/
HIV
/
Programas Nacionais de Saúde
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
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Estudo prognóstico
/
Fatores de risco
País/Região como assunto:
América do Sul
/
Caribe Inglês
/
Suriname
Idioma:
Inglês
Ano de publicação:
2019
Tipo de documento:
Artigo