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Sequence variation among SARS-CoV-2 isolates in Taiwan
Yu-Nong Gong; Kuo-Chien Tsao; Mei-Jen Hsiao; Chung-Guei Huang; Peng-Nien Huang; Po-Wei Huang; Kuo-Ming Lee; Yi-Chun Liu; Shu-Li Yang; Rei-Lin Kuo; Ming-Tsan Liu; Ji-Rong Yang; Cheng-Hsun Chiu; Cheng-Ta Yang; Shin-Ru Shih; Guang-Wu Chen.
Afiliação
  • Yu-Nong Gong; Chang Gung University
  • Kuo-Chien Tsao; Linkou Chang Gung Memorial Hospital
  • Mei-Jen Hsiao; Linkou Chang Gung Memorial Hospital
  • Chung-Guei Huang; Linkou Chang Gung Memorial Hospital
  • Peng-Nien Huang; Chang Gung University
  • Po-Wei Huang; Linkou Chang Gung Memorial Hospital
  • Kuo-Ming Lee; Chang Gung University
  • Yi-Chun Liu; Linkou Chang Gung Memorial Hospital
  • Shu-Li Yang; Linkou Chang Gung Memorial Hospital
  • Rei-Lin Kuo; Chang Gung University
  • Ming-Tsan Liu; Taiwan Centers for Disease Control
  • Ji-Rong Yang; Taiwan Centers for Disease Control
  • Cheng-Hsun Chiu; Linkou Chang Gung Memorial Hospital
  • Cheng-Ta Yang; Linkou Chang Gung Memorial Hospital
  • Shin-Ru Shih; Chang Gung University
  • Guang-Wu Chen; Chang Gung University
Preprint em Inglês | bioRxiv | ID: ppbiorxiv-014290
ABSTRACT
Taiwan experienced two waves of imported cases of coronavirus disease 2019 (COVID-19), first from China in January to late February, followed by those from other countries starting in early March. Additionally, several cases could not be traced to any imported cases and were suspected as sporadic local transmission. Twelve full viral genomes were determined in this study by Illumina sequencing either from virus isolates or directly from specimens, among which 5 originated from clustered infections. Phylogenetic tree analysis revealed that these sequences were in different clades, indicating that no major strain has been circulating in Taiwan. A deletion in open reading frame 8 was found in one isolate. Only a 4-nucleotide difference was observed among the 5 genomes from clustered infections.
Licença
cc_no
Texto completo: Disponível Coleções: Preprints Base de dados: bioRxiv Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: bioRxiv Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
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