Your browser doesn't support javascript.
loading
The emergence of inter-clade hybrid SARS-CoV-2 lineages revealed by 2D nucleotide variation mapping
Hai-Long Wang.
Afiliação
  • Hai-Long Wang; Mayo Clinic
Preprint em En | PREPRINT-BIORXIV | ID: ppbiorxiv-338038
ABSTRACT
I performed whole-genome sequencing on SARS-CoV-2 collected from COVID-19 samples at Mayo Clinic Rochester in mid-April, 2020, generated 85 consensus genome sequences and compared them to other genome sequences collected worldwide. I proposed a novel illustrating method using a 2D map to display populations of co-occurring nucleotide variants for intra- and inter-viral clades. This method is highly advantageous for the new era of "big-data" when high-throughput sequencing is becoming readily available. Using this method, I revealed the emergence of inter-clade hybrid SARS-CoV-2 lineages that are potentially caused by homologous genetic recombination.
Licença
cc_by_nd
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-BIORXIV Idioma: En Ano de publicação: 2020 Tipo de documento: Preprint
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-BIORXIV Idioma: En Ano de publicação: 2020 Tipo de documento: Preprint