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Comparison of SARS-CoV-2 VOC 202012/01 (UK variant) and D614G variant transmission by different routes in Syrian hamsters
Sreelekshmy Mohandas; Pragya Yadav; Dimpal Nyayanit; Anita Shete-Aich; Prasad Sarkale; Supriya Hundekar; Sanjay Kumar; Kavita Lole.
Afiliação
  • Sreelekshmy Mohandas; ICMR-National Institute of Virology
  • Pragya Yadav; ICMR-National Institute of Virology
  • Dimpal Nyayanit; ICMR-National Institute of Virology
  • Anita Shete-Aich; ICMR-National Institute of Virology
  • Prasad Sarkale; ICMR-National Institute of Virology
  • Supriya Hundekar; ICMR-National Institute of Virology
  • Sanjay Kumar; Department of Neurosurgery, Command Hospital (Southern Command), Armed Forces Medical College, Pune
  • Kavita Lole; ICMR-National Institute of Virology
Preprint em En | PREPRINT-BIORXIV | ID: ppbiorxiv-437153
ABSTRACT
Many SARS-CoV-2 variants of concern has been reported recently which were linked to increased transmission. In our earlier study on virus shedding using VOC 202012/01(UK variant) and D614G variant in hamster model, we observed significantly higher viral RNA shedding through nasal wash in case of UK variant. Hence, we compared the transmission of both the UK and D614G variant by various routes in Syrian hamsters to understand whether the high viral RNA shedding could enhance the transmission efficiency of the variant. The current study demonstrated comparable transmission efficiency of both UK and D614G variants of SARS-CoV-2 in Syrian hamsters.
Licença
cc_by_nc_nd
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-BIORXIV Idioma: En Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: 1 Coleções: 09-preprints Base de dados: PREPRINT-BIORXIV Idioma: En Ano de publicação: 2021 Tipo de documento: Preprint