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Forecasting COVID-19 and Analyzing the Effect of Government Interventions
Michael L Li; Hamza Tazi Bouardi; Omar Skali Lami; Thomas A Trikalinos; Nikolaos K Trichakis; Dimitris Bertsimas.
Afiliação
  • Michael L Li; Massachusetts Institute of Technology
  • Hamza Tazi Bouardi; Massachusetts Institute of Technology
  • Omar Skali Lami; Massachusetts Institute of Technology
  • Thomas A Trikalinos; Brown University
  • Nikolaos K Trichakis; Massachusetts Institute of Technology
  • Dimitris Bertsimas; Massachusetts Institute of Technology
Preprint em Inglês | medRxiv | ID: ppmedrxiv-20138693
ABSTRACT
One key question in the ongoing COVID-19 pandemic is understanding the impact of government interventions, and when society can return to normal. To this end, we develop DELPHI, a novel epidemiological model that captures the effect of under-detection and government intervention. We applied DELPHI across 167 geographical areas since early April, and recorded 6% and 11% two-week out-of-sample Median Absolute Percentage Error on cases and deaths respectively. Furthermore, DELPHI successfully predicted the large-scale epidemics in many areas months before, including US, UK and Russia. Using our flexible formulation of government intervention in DELPHI, we are able to understand how government interventions impacted the pandemics spread. In particular, DELPHI predicts that in absence of any interventions, over 14 million individuals would have perished by May 17th, while 280,000 current deaths could have been avoided if interventions around the world started one week earlier. Furthermore, we find mass gathering restrictions and school closings on average reduced infection rates the most, at 29.9 {+/-} 6.9% and 17.3 {+/-} 6.7%, respectively. The most stringent policy, stay-at-home, on average reduced the infection rate by 74.4 {+/-} 3.7% from baseline across countries that implemented it. We also illustrate how DELPHI can be extended to provide insights on reopening societies under different policies.
Licença
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Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo prognóstico Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo prognóstico Idioma: Inglês Ano de publicação: 2020 Tipo de documento: Preprint
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