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Using proper mean generation intervals in modelling of COVID-19
Xiujuan Tang; Salihu S Musa; Shi Zhao; Daihai He.
Afiliação
  • Xiujuan Tang; Shenzhen Center for Disease Control and Prevention
  • Salihu S Musa; Hong Kong Polytechnic University
  • Shi Zhao; Chinese University of Hong Kong
  • Daihai He; Hong Kong Polytechnic University
Preprint em Inglês | medRxiv | ID: ppmedrxiv-21254307
ABSTRACT
In susceptible-exposed-infectious-recovered (SEIR) epidemic models, with the exponentially distributed duration of exposed/infectious statuses, the mean generation interval (GI, time lag between infections of a primary case and its secondary case) equals the mean latent period (LP) plus the mean infectious period (IP). It was widely reported that the GI for COVID-19 is as short as 5 days. However, many works in top journals used longer LP or IP with the sum (i.e., GI), e.g., > 7 days. This discrepancy will lead to overestimated basic reproductive number, and exaggerated expectation of infectious attack rate and control efficacy, since all these quantities are functions of basic reproductive number. We argue that it is important to use suitable epidemiological parameter values.
Licença
cc_by_nc_nd
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Estudo observacional Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Estudo observacional Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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