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National and subnational short-term forecasting of COVID-19 in Germany and Poland, early 2021
Johannes Bracher; Daniel Wolffram; Jannik Deuschel; Konstantin Goergen; Jakob L. Ketterer; Alexander Ullrich; Sam Abbott; Maria V Barbarossa; Dimitris Bertsimas; Sangeeta Bhatia; Marcin Bodych; Nikos I Bosse; Jan P Burgard; Lauren Castro; Geoffrey Fairchild; Jochen Fiedler; Jan Fuhrmann; Sebastian Funk; Anna Gambin; Krzysztof Gogolewski; Stefan Heyder; Thomas Hotz; Yuri Kheifetz; Holger Kirsten; Tyll Krueger; Ekaterina Krymova; Neele Leithaeuser; Michael L Li; Jan H Meinke; Isaac J Michaud; Blazej Miasojedow; Jan Mohring; Pierre Nouvellet; Jedrzej M Nowosielski; Tomasz Ozanski; Maciej Radwan; Franciszek Rakowski; Markus Scholz; Saksham Soni; Ajitesh Srivastava; Tilmann Gneiting; Melanie Schienle.
Afiliação
  • Johannes Bracher; Karlsruhe Institute of Technology
  • Daniel Wolffram; Karlsruhe Institute of Technology
  • Jannik Deuschel; Karlsruhe Institute of Technology
  • Konstantin Goergen; Karlsruhe Institute of Technology
  • Jakob L. Ketterer; Karlsruhe Institute of Technology
  • Alexander Ullrich; Robert Koch Institute
  • Sam Abbott; London School of Hygiene and Tropical Medicine
  • Maria V Barbarossa; Frankfurt Institute of Advanced Studies
  • Dimitris Bertsimas; Sloan School of Management, Massachusetts Institute of Technology
  • Sangeeta Bhatia; Imperial College London
  • Marcin Bodych; Wroclaw University of Science and Technology
  • Nikos I Bosse; London School of Hygiene and Tropical Medicine
  • Jan P Burgard; Trier University
  • Lauren Castro; Los Alamos National Laboratory
  • Geoffrey Fairchild; Los Alamos National Laboratory
  • Jochen Fiedler; Fraunhofer Institute for Industrial Mathematics (ITWM)
  • Jan Fuhrmann; University of Heidelberg
  • Sebastian Funk; London School of Hygiene and Tropical Medicine
  • Anna Gambin; Faculty of Mathematics, Informatics, and Mechanics, University of Warsaw
  • Krzysztof Gogolewski; Faculty of Mathematics, Informatics, and Mechanics, University of Warsaw
  • Stefan Heyder; Technische Universitaet Ilmenau
  • Thomas Hotz; Technische Universitaet Ilmenau
  • Yuri Kheifetz; University of Leipzig
  • Holger Kirsten; University of Leipzig
  • Tyll Krueger; Wroclaw University of Science and Technology, Wroclaw, Poland
  • Ekaterina Krymova; Swiss Data Science Center, EPFL & ETHZ
  • Neele Leithaeuser; Fraunhofer Institute for Industrial Mathematics (ITWM)
  • Michael L Li; Operations Research Center, Massachusetts Institute of Technology
  • Jan H Meinke; Juelich Supercomputing Centre
  • Isaac J Michaud; Los Alamos National Laboratory
  • Blazej Miasojedow; Faculty of Mathematics, Informatics, and Mechanics, University of Warsaw
  • Jan Mohring; Fraunhofer Institute for Industrial Mathematics (ITWM)
  • Pierre Nouvellet; University of Sussex
  • Jedrzej M Nowosielski; Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw
  • Tomasz Ozanski; Wroclaw University of Science and Technology, Wroclaw, Poland
  • Maciej Radwan; Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw
  • Franciszek Rakowski; Interdisciplinary Centre for Mathematical and Computational Modelling, University of Warsaw
  • Markus Scholz; University of Leipzig
  • Saksham Soni; Operations Research Center, Massachusetts Institute of Technology
  • Ajitesh Srivastava; University of Southern California
  • Tilmann Gneiting; Heidelberg Institute of Technology
  • Melanie Schienle; Karlsruhe Institute of Technology
Preprint em Inglês | medRxiv | ID: ppmedrxiv-21265810
ABSTRACT
BackgroundDuring the COVID-19 pandemic there has been a strong interest in forecasts of the short-term development of epidemiological indicators to inform decision makers. In this study we evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland for the period from January through April 2021. MethodsWe evaluate probabilistic real-time predictions of confirmed cases and deaths from COVID-19 in Germany and Poland. These were issued by 15 different forecasting models, run by independent research teams. Moreover, we study the performance of combined ensemble forecasts. Evaluation of probabilistic forecasts is based on proper scoring rules, along with interval coverage proportions to assess forecast calibration. The presented work is part of a pre-registered evaluation study and covers the period from January through April 2021. ResultsWe find that many, though not all, models outperform a simple baseline model up to four weeks ahead for the considered targets. Ensemble methods (i.e., combinations of different available forecasts) show very good relative performance. The addressed time period is characterized by rather stable non-pharmaceutical interventions in both countries, making short-term predictions more straightforward than in previous periods. However, major trend changes in reported cases, like the rebound in cases due to the rise of the B.1.1.7 (alpha) variant in March 2021, prove challenging to predict. ConclusionsMulti-model approaches can help to improve the performance of epidemiological forecasts. However, while death numbers can be predicted with some success based on current case and hospitalization data, predictability of case numbers remains low beyond quite short time horizons. Additional data sources including sequencing and mobility data, which were not extensively used in the present study, may help to improve performance. Plain language summaryThe goal of this study is to assess the quality of forecasts of weekly case and death numbers of COVID-19 in Germany and Poland during the period of January through April 2021. We focus on real-time forecasts at time horizons of one and two weeks ahead created by fourteen independent teams. Forecasts are systematically evaluated taking uncertainty ranges of predictions into account. We find that combining different forecasts into ensembles can improve the quality of predictions, but especially case numbers proved very challenging to predict beyond quite short time windows. Additional data sources, in particular genetic sequencing data, may help to improve forecasts in the future.
Licença
cc_by_nc
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
Texto completo: Disponível Coleções: Preprints Base de dados: medRxiv Tipo de estudo: Experimental_studies / Estudo prognóstico Idioma: Inglês Ano de publicação: 2021 Tipo de documento: Preprint
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