Effects of single-dose praziquantel on morbidity and mortality resulting from intestinal schistosomiasis
(East. Mediterr. health j).
em Inglês
| WHO IRIS
| ID: who-118947
Biblioteca responsável:
CH1.1
ABSTRACT
The long-term effect of single-dose praziquantel on morbidity and mortality from Schistosoma mansoni was investigated in surveys in 1987 and 1994 in central Sudan. Prevalence of infection dropped from 53% to 34%, and intensity of infection [400 eggs/g of faeces] from 31% to 18%. There was a reduction in hepatomegaly and hepatosplenomegaly, although splenomegaly alone was unchanged. Prevalence of periportal fibrosis decreased from 14% to 10%. Endoscopic investigation of patients with fibrosis showed a reduction in oesophageal varices from 47% to 30%. Mortality due to bleeding varices was high [community-wide, up to 11/100 infected patients with bleeding]. Thus praziquantel mass treatment can be spaced to a much longer period, reducing the expense of treatment, delivery and distribution
Texto completo:
Disponível
Coleções:
Bases de dados de organismos internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
/
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
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Helmintíase
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Doenças Negligenciadas
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Esquistossomose
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Zoonoses
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Cirrose
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Doenças do Sistema Digestório
Base de dados:
WHO IRIS
Assunto principal:
Praziquantel
/
Esquistossomose mansoni
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Varizes Esofágicas e Gástricas
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Prevalência
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Cirrose Hepática
Idioma:
Inglês
Revista:
East. Mediterr. health j
Ano de publicação:
2000