Biochemical effects of vinyl chloride monomer on the liver of occupationally exposed workers
(East. Mediterr. health j).
em Inglês
| WHO IRIS
| ID: who-118955
Biblioteca responsável:
CH1.1
ABSTRACT
We investigated the effects of vinyl chloride monomer exposure on the liver of 86 workers by measuring beta-glucuronidase, arylsulfatase A, adenosine deaminase, 5'-nucleotidase and routine liver function enzymes in the sera of the workers. In 21 of them, three or more of these parameters were raised, with a significant decrease in the level of blood glutathione and a significant increase in the enzyme activity level of glutathione S-transferase. Of these 21 workers, 14 had fatty liver infiltration, 8 of whom were also suffering from liver enlargement. Also, 4 workers had liver enlargement without fatty infiltration and 3 had enlarged spleens. The study highlights the need for vigilance in environmental monitoring and medical surveillance of workers exposed to this chemical
Texto completo:
Disponível
Coleções:
Bases de dados de organismos internacionais
Contexto em Saúde:
ODS3 - Meta 3.9 Reduzir as mortes por produtos químicos y contaminação do ar, água e solo
/
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Exposições Ocupacionais
/
Meta 3.9: Reduzir o número de mortes por produtos químicos perigosos e contaminação do ar e água do solo
Base de dados:
WHO IRIS
Assunto principal:
Cloreto de Vinil
/
Exposição Ocupacional
/
Fígado
Idioma:
Inglês
Revista:
East. Mediterr. health j
Ano de publicação:
2000