Molecular epidemiology and evolution of A[H1N1] pdm09 and H3N2 viruses in Jordan, 2011-2013
East. Mediterr. health j
; 22(7): 490-498, 2016-07.
Article
em En
| WHOLIS
| ID: who-260100
Biblioteca responsável:
CH1.1
ABSTRACT
Understanding the genetic evolution of A [H1N1]pdm09 and H3N2 viruses can help better select strains to be included in the annual influenza vaccine. There is little information on their evolution in Jordan so this study investigated the genetic and antigenic variability of A[H1N1]pdm09 and H3N2 viruses in Jordan by performing phylogenetic and genetic analyses of the HA and NA genes of A[H1N1]pdm09 and H3N2 viruses between 2011 and 2013. The full HA and NA genes of 16 H1N1-positive samples obtained in our study and 21 published HA sequences and 20 published NA sequences from Jordanian viruses that were available on online gene databases were analysed. For H3N2, we generated 20 HA and 19 NA sequences and included 19 published HA and NA sequences each in the analysis. Jordanian H1N1 viruses had mutations that are characteristic of antigenic group 6 while H3N2 virus mutations belonged to group 3. No markers of resistance to oseltamivir were detected. The individual mutations are described in detail
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Coleções:
04-international_org
Base de dados:
WHOLIS
Assunto principal:
Vacinas contra Influenza
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Reação em Cadeia da Polimerase
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Doenças Transmissíveis
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Estudos Prospectivos
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Estudos de Coortes
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Bases de Dados Genéticas
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Vírus da Influenza A Subtipo H1N1
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Vírus da Influenza A Subtipo H3N2
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Oseltamivir
Idioma:
En
Revista:
East. Mediterr. health j
Ano de publicação:
2016
Tipo de documento:
Article