Evodiamine induces apoptosis of leukemia cell line K562 VIA modulation of TRIB2/AKT pathway

Feng-Lin MOU; Bei-Zhong LIU; Jian LI; Liang ZHONG; Jiao YE; Bei-Zhong LIU; Li-Hua YU; Wen-Ran DAN; Ling XIONG

Evodiamine induces apoptosis of leukemia cell line K562 VIA modulation of TRIB2/AKT pathway / 中国药理学通报

Feng-Lin MOU; Bei-Zhong LIU; Jian LI; Liang ZHONG; Jiao YE; Bei-Zhong LIU; Li-Hua YU; Wen-Ran DAN; Ling XIONG.

Chinese Pharmacological Bulletin ; (12): 118-124, 2021.

Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-1014302

Biblioteca responsável: WPRO

ABSTRACT

ABSTRACT

Aim To investigate the effects of Evodiamine (EVO) on proliferation and apoptosis of human leukemia cell line K562 and its potential mechanisms. Methods K562 cells were treated with EVO at different concentrations (0, 1, 2, 4, 8, 16, 32, 64 jxmol • L

AKT; apoptosis; evodiamine; K562 cell; proliferation suppression; TRIB2

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Texto completo: Disponível Base de dados: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Pharmacological Bulletin Ano de publicação: 2021 Tipo de documento: Artigo

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