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Epigenetic regulation in pulmonary heart disease by non-coding RNA / 中国药理学通报
Chinese Pharmacological Bulletin ; (12): 317-322, 2021.
Article em Zh | WPRIM | ID: wpr-1014336
Biblioteca responsável: WPRO
ABSTRACT
Pulmonary heart disease (PHD) is a common cardiovascular disease in China, with high mortality ratein its late stage.Currently, PHD treatments are mainly to delay the disease progression, which cannot effectively improve and cure the disease.Consequently, it is in urgent need to find a new treatment for PHD.Epigenetic regulation plays an important role in the occurrence and pathological process of diseases, which provides a novel idea of developing new drugs by regulating non-coding RNA(ncRNA).However, ncRNA studies in PHD are at the stage of few and shallow, stray and scattered.Therefore, this review for the first time summarizes ncRNA related to various PHD phenotypes, and discusses the epigenetic regulation in PHD by ncRNA.
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Texto completo: 1 Base de dados: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Ano de publicação: 2021 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Ano de publicação: 2021 Tipo de documento: Article