Research progress on the relationship between miRNA and pathogenesis of cataract / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
; (12): 1064-1067, 2024.
Article
em Zh
| WPRIM
| ID: wpr-1032348
Biblioteca responsável:
WPRO
ABSTRACT
The microRNA(miRNA)is a widely present small non-coding RNA(ncRNA), with a length of 20-25 nucleotides. The miRNA in eye tissue plays crucial roles in normal eyes by participating in processes such as cell growth, proliferation, differentiation, and apoptosis. Cataracts are the main cause of blindness worldwide. Research has shown that miRNA is related to the occurrence and development of cataracts, and it has new application prospects as a potential target for the treatment and prevention of cataracts. This article reviews the relationship between miRNA and the occurrence and development of cataracts through several different pathogenesis mechanisms, including oxidative damage, apoptosis, autophagy, and epithelial mesenchymal transition(EMT).
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
International Eye Science
Ano de publicação:
2024
Tipo de documento:
Article