A Case of IgG4-Related Lung Disease Mimicking Non-Specific Interstitial Pneumonia / 대한내과학회지
Korean Journal of Medicine
; : 308-312, 2015.
Article
em Ko
| WPRIM
| ID: wpr-103789
Biblioteca responsável:
WPRO
ABSTRACT
Immunoglobulin (Ig) G4-related disease is a recently described systemic inflammatory disease characterized by high serum IgG4 concentrations and sclerosing inflammation of numerous IgG4-positive plasma cells that responds favorably to steroid treatment. Although initial description of this disorder focused on its pancreatic presentation, it has become apparent that it is a systemic disease. In this report, we describe a case of IgG4-related lung disease presenting as non-specific interstitial pneumonia in a 78-year-old male with interstitial lung disease. Pathological examination through video-assisted thoracic surgery showed a non-specific interstitial pneumonia pattern and numerous (> 50/high-power field) infiltrating IgG4-positive plasma cells. Laboratory tests also revealed a high serum IgG4 concentration. Prednisolone therapy was initiated and his symptoms and reticular opacity improved after two months of treatment.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Plasmócitos
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Imunoglobulina G
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Imunoglobulinas
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Prednisolona
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Doenças Pulmonares Intersticiais
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Cirurgia Torácica Vídeoassistida
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Inflamação
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Pneumopatias
Limite:
Aged
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Humans
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Male
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2015
Tipo de documento:
Article