An Epidemiological Analysis of Hepatitis A Virus Serologic Markers during the Recent Four Years in Korea / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 563-569, 2009.
Article
em Ko
| WPRIM
| ID: wpr-106758
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: To establish effective preventive measures for hepatitis A virus (HAV) infection, a nationwide epidemiologic study on seroprevalence of anti-HAV and the disease prevalence is needed. The aim of this study was to analyze the recent sero-epidemiological changes of hepatitis A markers in Korea. METHODS: The results of 11,068 anti-HAV total and 32,360 anti-HAV IgM tests by electro-chemiluminescence immunoassay (ECLIA) that had been requested in recent four years (2005-2008) to a reference medical laboratory from 1,699 institutions nationwide were retrospectively analyzed according to the distribution of year, sex, and age groups. RESULTS: The overall positive rate of anti-HAV total was 62.8%. The overall positive rate of anti-HAV IgM was 11.0%, showing a significantly increasing trend by year: 7.7%, 10.9%, 8.9%, and 14.3% in 2005, 2006, 2007, and 2008, respectively (P or =21 yr. Conclusion: In accordance with a decreasing sero-positivity of anti-HAV total, the prevalence of acute hepatitis A virus infection has been considerably increased during the recent four years in the age groups of > or =21 yr. The results of this study could be used effectively as a basic data for establishing effective preventive measures for hepatitis A including vaccination in these susceptible age groups.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fatores de Tempo
/
Imunoglobulina M
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Ensaio de Imunoadsorção Enzimática
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Biomarcadores
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Fatores Sexuais
/
Estudos Retrospectivos
/
Vírus da Hepatite A
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Anticorpos Anti-Hepatite A
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República da Coreia
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Hepatite A
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2009
Tipo de documento:
Article