Two Cases of Eosinophilic Fasciitis
Annals of Dermatology
; : 81-84, 2011.
Article
em En
| WPRIM
| ID: wpr-110495
Biblioteca responsável:
WPRO
ABSTRACT
Eosinophic fasciitis (EF) is an uncommon connective tissue disease characterized by scleroderma-like cutaneous changes, peripheral eosinophilia, hypergammaglobulinemia, and an elevated erythrocyte sedimentation rate (ESR). Typical histopathologic findings include chronic inflammatory infiltration affecting the deep fascia with lymphocytes, histiocytes, and occasionally eosinophils. We report two cases of EF, the first of which is a 36-year-old man with a tender brownish induration on both forearms, for 2 months. Histopathologic examination showed fibrotic fascia with a mixed inflammatory cell infiltration. The second case is a 52-year-old woman with a symmetrical painful swelling and skin induration on both forearms, for 4 months. A deep biopsy demonstrated chronic inflammatory cell infiltration and hyaline degeneration in the fascia. Increased signal intensity in the fascia and tendon sheath was shown on magnetic resonance imaging. In laboratory examination, mild eosinophilia was found in both cases. Both patients had a history of physical activity (weight training and excessive housework, respectively) and showed marked improvement with high doses of oral prednisolone for several months.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Pele
/
Tendões
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Biópsia
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Sedimentação Sanguínea
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Prednisolona
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Imageamento por Ressonância Magnética
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Linfócitos
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Doenças do Tecido Conjuntivo
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Eosinofilia
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Eosinófilos
Limite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Annals of Dermatology
Ano de publicação:
2011
Tipo de documento:
Article