Therapeutic Plasma Exchange for a Patient with Severe Cold Agglutinin Disease / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 75-80, 2015.
Article
em Ko
| WPRIM
| ID: wpr-114279
Biblioteca responsável:
WPRO
ABSTRACT
Cold agglutinin disease is a kind of autoimmune hemolytic anemia, caused by cold agglutinin, serum autoantibodies activated at reduced body temperatures to produce red blood cell agglutination and hemolysis. In this paper we described a case of severe hemolytic anemia in a cold agglutinin disease patient treated with therapeutic plasma exchange. Therapeutic plasma exchanges were performed four times every other day. Over the same period, a total of 8 units of washed red blood cells were transfused. Then hemoglobin was increased from 4.0 g/dL to 7.8 g/dL. On the 12th hospital day hemoglobin level was decreased again to 4.2 g/dL and fludarabine chemotherapy was started on the 14th hospital day. The patient's symptoms were relieved and she was discharged on the 30th hospital day. As in this case, therapeutic plasma exchange could be considered as secondary therapy for temporary improvement of acute severe hemolytic anemia in cold agglutinin disease.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Troca Plasmática
/
Autoanticorpos
/
Temperatura Corporal
/
Aglutinação
/
Tratamento Farmacológico
/
Eritrócitos
/
Hemólise
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Anemia Hemolítica
/
Anemia Hemolítica Autoimune
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Blood Transfusion
Ano de publicação:
2015
Tipo de documento:
Article