Two Cases of Gastric Marginal Zone B Cell Lymphoma Treated with a Single Agent Chemotherapy / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
; : 175-180, 2010.
Article
em Ko
| WPRIM
| ID: wpr-118156
Biblioteca responsável:
WPRO
ABSTRACT
Gastric marginal zone B cell lymphoma of the MALT type (MALT lymphoma) is usually accompanied by a Helicobacter pylori (H. pylori) infection. Most gastric MALT lymphomas regress after the eradication of H. pylori. Therefore, H. pylori eradication therapy is an effective first-line treatment for gastric MALT lymphoma. A second-line treatment for patients who fail to respond to eradication therapy, including radiotherapy and chemotherapy, produces a good response and survival rate. We encountered 2 cases of H. pylori eradication-resistant gastric MALT lymphoma, which were treated with cyclophosphamide monotherapy. A complete response was obtained in both cases after a treatment duration of 3 months and remission continued for 15 and 18 months, respectively. Treatment-related toxicity was mild. Oral monochemotherapy might be an alternative, effective and safe treatment modality for patients with gastric MALT lymphoma who are resistant to H. pylori eradication therapy.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Estômago
/
Taxa de Sobrevida
/
Helicobacter pylori
/
Linfoma de Zona Marginal Tipo Células B
/
Ciclofosfamida
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Gastrointestinal Endoscopy
Ano de publicação:
2010
Tipo de documento:
Article
País de publicação:
COREA DEL SUR
/
COREIA DO SUL
/
KR
/
SOUTH KOREA