A Case of Fasciola hepatica Infection Mimicking Cholangiocarcinoma and ITS-1 Sequencing of the Worm
The Korean Journal of Parasitology
; : 193-196, 2014.
Article
em En
| WPRIM
| ID: wpr-121888
Biblioteca responsável:
WPRO
ABSTRACT
Fascioliasis is a zoonotic infection caused by Fasciola hepatica or Fasciola gigantica. We report an 87-year-old Korean male patient with postprandial abdominal pain and discomfort due to F. hepatica infection who was diagnosed and managed by endoscopic retrograde cholangiopancreatography (ERCP) with extraction of 2 worms. At his first visit to the hospital, a gallbladder stone was suspected. CT and magnetic retrograde cholangiopancreatography (MRCP) showed an intraductal mass in the common bile duct (CBD) without proximal duct dilatation. Based on radiological findings, the presumed diagnosis was intraductal cholangiocarcinoma. However, in ERCP which was performed for biliary decompression and tissue diagnosis, movable materials were detected in the CBD. Using a basket, 2 living leaf-like parasites were removed. The worms were morphologically compatible with F. hepatica. To rule out the possibility of the worms to be another morphologically close species, in particular F. gigantica, 1 specimen was processed for genetic analysis of its ITS-1 region. The results showed that the present worms were genetically identical (100%) with F. hepatica but different from F. gigantica.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Sequência de Bases
/
Análise de Sequência de DNA
/
Colangiocarcinoma
/
Ducto Colédoco
/
DNA de Helmintos
/
DNA Intergênico
/
Colangiopancreatografia por Ressonância Magnética
/
Diagnóstico Diferencial
/
Fasciola hepatica
/
Fasciolíase
Tipo de estudo:
Diagnostic_studies
Limite:
Aged80
/
Animals
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
The Korean Journal of Parasitology
Ano de publicação:
2014
Tipo de documento:
Article