Does Lymphocytic Colitis Always Present with Normal Endoscopic Findings?
Gut and Liver
; : 197-201, 2015.
Article
em En
| WPRIM
| ID: wpr-136387
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS: Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, several cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, clinical, and histopathologic features of LC with MLs. METHODS: A total of 14 patients with LC who were diagnosed between 2005 and 2010 were enrolled in the study. Endoscopic, clinical, and histopathologic findings were compared retrospectively according to the presence or absence of MLs. RESULTS: MLs were observed in seven of the 14 LC cases. Six of the MLs exhibited hypervascularity, three exhibited exudative bleeding and one exhibited edema. The patients with MLs had more severe diarrhea and were taking aspirin or proton pump inhibitors. More intraepithelial lymphocytes were observed during histologic examination in the patients with MLs compared to the patients without MLs, although this difference was not significant. The numbers of mononuclear cells and neutrophils in the lamina propria were independent of the presence or absence of MLs. CONCLUSIONS: LC does not always present with normal endoscopic findings. Hypervascularity and exudative bleeding are frequent endoscopic findings in patients with MLs.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Estudos Retrospectivos
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Colonoscopia
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Colo
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Colite Colagenosa
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Colite Linfocítica
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Diagnóstico Diferencial
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Diarreia
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Mucosa Intestinal
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Gut and Liver
Ano de publicação:
2015
Tipo de documento:
Article