Treatment Outcome of Metastatic Carcinoma of Cervical Lymph Node from an Unknown Primary / 대한방사선종양학회지
The Journal of the Korean Society for Therapeutic Radiology and Oncology
; : 137-142, 2005.
Article
em En
| WPRIM
| ID: wpr-139471
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: To analyze the outcome of radiation therapy for patients with a metastatic carcinoma of cervical lymph nodes from an unknown primary (MUO), and identify the prognostic factors for these patients. MATERIALS AND METHODS: Between July 1981 and June 1999, 39 patients with MUO underwent radiation therapy with curative intent. Twelve patients were treated with radiation therapy alone (Group 1), 8 with neoadjuvant chemotherapy followed by radiation therapy (Group 2), and 19 with either an excision or neck dissection and postoperative radiation therapy (Group 3). There were 31 males and 8 females, with a median age of 55 years, ranging from 25 to 77 ears. The median duration of follow-up was 38 months, ranging from 3 to 249 months. RESULTS: The 5-year overall survival rate was 55%. According to the treatment modality, the 5-year disease-free survival rates of Groups 1, 2 and 3 were 48, 19 and 75%, respectively (p=0.0324). In addition to the treatment modality, the appearance of the primary site was a significant prognostic factor for disease-free survival (p=0.0085). CONCLUSION: Surgical resection and radiation therapy achieves a superior disease-free survival compared to radiation therapy alone, either with or without chemotherapy. Further investigation is needed to evaluate the role of chemotherapy in the treatment of MUO.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Esvaziamento Cervical
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Taxa de Sobrevida
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Seguimentos
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Resultado do Tratamento
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Intervalo Livre de Doença
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Tratamento Farmacológico
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Orelha
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Linfonodos
Tipo de estudo:
Observational_studies
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Prognostic_studies
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
The Journal of the Korean Society for Therapeutic Radiology and Oncology
Ano de publicação:
2005
Tipo de documento:
Article