Usefulness of 18F-FDG PET/CT in the Diagnosis of Cervical Lymph Node Metastases of Head and Neck Cancer / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
; : 269-277, 2005.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-145410
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
This study evaluated the diagnostic value of 18F-FDG PET/CT in detecting cervical lymph node metastases in head and neck cancer patients. MATERIALS ANDMETHODS:
The patients were divided into two groups, 46 patients underwent PET/CT scan for initial staging before surgery, and 20 patients for restaging of recurrence after primary treatment. Increased FDG uptakes in cervical lymph nodes were evaluated retrospectively and correlated with the histopathologic results.RESULTS:
In the initial staging group, 21 lymph nodes were detected by PET/CT in 15 patients. 20 lymph nodes were confirmed as metastases with a mean peak SUV of 5.84, and the remaining one lymph node was an inflammatory lesion, with a peak SUV of 2.75. Seven metastatic lymph nodes were reported only by histopathology. The sensitivity, specificity, positive predictive value and negative predictive value were 74.0%, 99.6%, 95.2% and 97.3%, respectively. In the recurrence group, 11 lymph nodes were detected in 9 patients, and 8 nodes were true positive, with a mean peak SUV of 5.65. The other three were inflammatous lymph nodes, and the peak SUVs were 2.16, 2.94 and 3.53. One false negative lymph node was reported. The sensitivity, specificity, positive predictive value and negative predictive value were 88.8%, 97.7%, 72.7% and 92.9%, respectively.CONCLUSIONS:
FDG-PET/CT shows higher positive predictive value in the initial staging group, and better sensitivity in the recurrence group. Therefore PET/CT could be useful for both initial staging and restaging of recurrent cervical lymph node metastases.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Recidiva
/
Estudos Retrospectivos
/
Sensibilidade e Especificidade
/
Fluordesoxiglucose F18
/
Diagnóstico
/
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada
/
Cabeça
/
Neoplasias de Cabeça e Pescoço
/
Linfonodos
/
Metástase Neoplásica
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Nuclear Medicine
Ano de publicação:
2005
Tipo de documento:
Artigo