Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 463-468, 2015.
Article
em En
| WPRIM
| ID: wpr-149059
Biblioteca responsável:
WPRO
ABSTRACT
Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fumaça
/
Privação de Água
/
Biópsia
/
Imageamento por Ressonância Magnética
/
Fumar
/
Histiocitose de Células de Langerhans
/
Seguimentos
/
Abandono do Hábito de Fumar
/
Tosse
/
Diabetes Insípido Neurogênico
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Tuberculosis and Respiratory Diseases
Ano de publicação:
2015
Tipo de documento:
Article