Comparison of Erythropoietic Effect between Epoetin-alpha and Darbepoetin-alpha in Hemodialysis Patients: A Randomized Crossover Study / 대한신장학회지
Korean Journal of Nephrology
; : 450-455, 2009.
Article
em Ko
| WPRIM
| ID: wpr-158412
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
We aim to compare the erythropoietic effects of epoetin-alpha (EA, 4000 IU SC thrice a week) with those of darbepoetin-alpha (DA, 60ug IV weekly, conversion rate to EA=2001).METHODS:
Forty one stable hemodialysis patients were enrolled in this randomized crossover study. After a washout period of erythropoietin stimulating agents (ESA), the patients with hemoglobin (Hb) level of 11.0 g/dL, we stopped ESA. When Hb level decreased to 30% change in EA efficiency relative to DA efficiency.CONCLUSION:
There was no significant difference in erythropoietic parameters for both EA and DA.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Reticulócitos
/
Proteínas Recombinantes
/
Hemoglobinas
/
Eritropoetina
/
Diálise Renal
/
Estudos Cross-Over
/
Epoetina alfa
/
Darbepoetina alfa
/
Anemia
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Nephrology
Ano de publicação:
2009
Tipo de documento:
Article