Effect of postmenopausal hormone replecement therapy on leptin level and body composition / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
; : 2109-2116, 2001.
Article
em Ko
| WPRIM
| ID: wpr-169203
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To compare the women who use postmenopausal hormone replacement therapy to never user for the serum leptin level and degree of obesity, then evaluate the precausing factor of postmenopausal obesity.METHOD:
We checked the serum leptin level, blood chemistry and body composition in three groups, two groups are postmenopause groups which is HRT user (n=125) and HRT never user (n=194), and the other is premenopause groups(n=82). We used SPSS and Excel for analyzed the difference between the groups.RESULT:
BMR is decreased after menopause, body fat ratio, abdominal fat ratio, BMI, leptin, sugar, and cholesterol level are increased after menopause. There is no difference between the postmenopausal HRT group and non-HRT group in body fat composition, abdominal fat ratio, BMI,BMR,AMC and leptin levels. Serum sugar level shows positive correlation with the leptin level in pre and postmenopausal women after exclude the effect of body fat ratio. Serum estradiol and leptin level shows positive correlation.(correlation coefficient 0.68 in postmenopausal non-HRT group and 0.735 in postmenopausal HRT group).CONCLUSION:
Serum estradiol and sugar level have some correlation with leptin level and leptin resistance in postmenopausal women, and decreased estradiol level caused obesity through increased leptin resistance.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Composição Corporal
/
Menopausa
/
Terapia de Reposição de Estrogênios
/
Química
/
Tecido Adiposo
/
Colesterol
/
Pré-Menopausa
/
Pós-Menopausa
/
Leptina
/
Gordura Abdominal
Limite:
Female
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2001
Tipo de documento:
Article