A Prospective Multicenter Study on the Etiological Analysis of Community-Acquired Pneumonia in Adult Patients in Korea: Detection of Mycoplasma pneumoniae and Chlamydia pneumoniae Infections / 감염
Korean Journal of Infectious Diseases
; : 15-23, 2001.
Article
em Ko
| WPRIM
| ID: wpr-169562
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
The purpose of this study is to develop rapid and sensitive method to detect M. pneumoniae and C. pneumoniae. In addition, we prospectively investigate the prevalence of M. pneumoniae and C. pneumoniae infections in community-acquried pneumonia.METHODS:
The nasopharyngeal aspirates were collected from July 1997 to April 2000. PCR or nested PCR techniques were used to detect causative agents. RFLP and nucleotide sequence analysis were performed to study molecular epidemiology. Furthermore, feasibility of one-step technique to detect two microorganisms was tested by use of multiplex PCR.RESULTS:
Of 250 clinical specimens, 23 (9.2%) specimens were positive for M. pneumoniae and 33 (13.2%) for C. pneumoniae, including one dual-infected specimen. Most M. pneumoniae infection occurred during the colder months of the year. C. pneumoniae infection was predominently found between December to February.CONCLUSION:
The result indicate that M. pneumoniae and C. pneumoniae infections are frequently found from patients with community-acquired pneumoniae.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pneumonia
/
Pneumonia por Mycoplasma
/
Polimorfismo de Fragmento de Restrição
/
Sequência de Bases
/
Chlamydia
/
Reação em Cadeia da Polimerase
/
Prevalência
/
Estudos Prospectivos
/
Chlamydophila pneumoniae
/
Epidemiologia Molecular
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
Limite:
Adult
/
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
Korean Journal of Infectious Diseases
Ano de publicação:
2001
Tipo de documento:
Article