A Case of Huntington's Disease with Generalized Seizure and Prominent Family History of the Disease / 신경정신의학
Journal of Korean Neuropsychiatric Association
; : 162-167, 2001.
Article
em Ko
| WPRIM
| ID: wpr-176477
Biblioteca responsável:
WPRO
ABSTRACT
Huntington's disease(HD), an autosomal dominant disorder, is characterized by progressive involuntary choreiform movement, psychiatric symptoms, and dementia. We experienced a 44-year-old male HD patient with prominent family history of the disease who showed dementia and involuntary movements including chorea. The diagnosis was made by clinical symptoms, family history of the disease, and brain MRI findings to show bicaudate atrophy and diffuse cortical atrophy with marked ventricualr dilatation. Interestingly, the patient frequently exhibited generalized tonic-clonic seizures. The seizures first appeared about 3 to 4 years after the onset of HD and were controlled with valproic acid. To our knowledge, this may be the first case of lateonset HD accompanied by generalized seizures and we report this case with literature review.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Atrofia
/
Convulsões
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Coreia
/
Ácido Valproico
/
Doença de Huntington
/
Discinesias
/
Demência
/
Diagnóstico
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
Ko
Revista:
Journal of Korean Neuropsychiatric Association
Ano de publicação:
2001
Tipo de documento:
Article
País de publicação:
COREA DEL SUR
/
COREIA DO SUL
/
KR
/
SOUTH KOREA