Serum adiponectin concentration according to visceral fat amount and its relationship of metabolic risk factors in premenopausal obese women / 대한내과학회지
Korean Journal of Medicine
; : 259-266, 2004.
Article
em Ko
| WPRIM
| ID: wpr-182254
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Adiponectin is adipose specific protein, which we considered to have metabolic and endocrine function in metabolic syndrome including obesity and insulin resistance. We measured serum adiponectin concentrations and compared them with body fat distribution and metabolic risk factors.METHODS:
112 premenopausal obese women were participated in this study. We measured plasma adiponectin concentration and metabolic risk factors such as fasting glucose and insulin, triglyceride, systolic blood pressure (SBP) and diastolic blood pressure (DBP). Subcutaneous adipose tissue area (SAT) and visceral adipose tissue area (VAT) were determined by computed tomography. Body mass index (BMI), waist to hip ratio (WHR) and homeostasis model assessment (HOMA-IR) were calculated.RESULTS:
Serum adiponectin concentration was inversely correlated with fasting insulin level, HOMA-IR, triglyceride, SBP, DBP, WHR, BMI and VAT, whereas HDL-cholesterol was positively correlated (all p values<0.05). VAT, SBP, and HDL-cholesterol level were independent variables of serum adiponectin concentrations.CONCLUSION:
The present study demonstrates that decreased plasma level of adiponectin is significantly associated with metabolic risk factors including body fat distribution; serum adiponectin level is determined by VAT, whereas SAT has no relation with serum adiponectin level.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Plasma
/
Triglicerídeos
/
Pressão Sanguínea
/
Resistência à Insulina
/
Índice de Massa Corporal
/
Fatores de Risco
/
Jejum
/
Relação Cintura-Quadril
/
Gordura Intra-Abdominal
/
Gordura Subcutânea
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2004
Tipo de documento:
Article
País de publicação:
COREA DEL SUR
/
COREIA DO SUL
/
KR
/
SOUTH KOREA