A Case of Ulcerative Colitis with Prolonged Remission Following Azathioprine-Induced Pancytopenia
Intestinal Research
; : 85-89, 2008.
Article
em Ko
| WPRIM
| ID: wpr-186562
Biblioteca responsável:
WPRO
ABSTRACT
Azathioprine (AZA) is widely used for the treatment of inflammatory bowel disease. Bone marrow suppression is a common side effect with AZA treatment. However, data from AZA trials has indicated that a leukocyte count less than 5,000/mm3 was a good predictor of induction and maintenance of remission. Moreover, there is evidence that eradication of sensitized leukocytes by leukapheresis or bone marrow transplantation improves inflammatory bowel disease. We report a case of a patient who had a chronic relapse of ulcerative colitis requiring the frequent use of systemic steroids, but presented prolonged remission following AZA-induced severe pancytopenia. Also colonoscopy showed accelerated healing of diffuse active ulcers following just recovery from pancytopenia.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pancitopenia
/
Recidiva
/
Esteroides
/
Azatioprina
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Úlcera
/
Medula Óssea
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Doenças Inflamatórias Intestinais
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Colite Ulcerativa
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Colonoscopia
/
Transplante de Medula Óssea
Limite:
Humans
Idioma:
Ko
Revista:
Intestinal Research
Ano de publicação:
2008
Tipo de documento:
Article
País de publicação:
COREA DEL SUR
/
COREIA DO SUL
/
KR
/
SOUTH KOREA