Clinical Characteristics of Patients with Adrenal Insufficiency in a General Hospital
Endocrinology and Metabolism
; : 83-89, 2017.
Article
em En
| WPRIM
| ID: wpr-194426
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: Adrenal insufficiency (AI) is a life-threatening disorder caused by the deficiency of adrenal steroid hormones. This retrospective cross-sectional study investigated the characteristics of patients with AI in Korea. METHODS: All consecutive patients with suspected AI who received care at a tertiary referral center in Korea in 2014 and underwent adrenocorticotropic hormone stimulation or insulin-tolerance testing were identified through a review of medical charts. Patients diagnosed with AI were enrolled. Their demographic, clinical, and treatment details were extracted. RESULTS: Of 771 patients with suspected AI, 183 (23.7%) received a definitive diagnosis. The most common reason for testing was the presence of suspicious AI-related symptoms (30.0%), followed by a history of steroid medications (23.5%). Their mean age was 66.7 years, and females predominated (67.8%). The most common symptoms were general weakness, anorexia, arthralgia, and fever. Approximately half (53.6%) had a history of steroid use. Hydrocortisone was the most common treatment (71.6%), with most patients taking a 30 mg dose (44.2%). The most common dose frequency was twice a day (78.6%). Fourteen patients were treated for adrenal crisis (n=10, 5.5%) or an intercurrent illness (n=4, 2.2%). CONCLUSION: AI may have been caused by steroid medication use in many of the patients included in this study. The detection of AI can be improved by careful history-taking and being alert to the possibility that a patient has used steroids.
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Base de dados:
WPRIM
Assunto principal:
Esteroides
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Características da População
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Hidrocortisona
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Anorexia
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Estudos Transversais
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Estudos Retrospectivos
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Insuficiência Adrenal
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Hormônio Adrenocorticotrópico
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Artralgia
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Diagnóstico
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Limite:
Female
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Endocrinology and Metabolism
Ano de publicação:
2017
Tipo de documento:
Article