Predictive factors of coronary lesion on preoperative diagnostic coronary angiography in korean patients with valvular heart disease / 대한내과학회지

ABSTRACT

BACKGROUND: The preoperative coronary angiography is required in some patients underwent valvular surgery. The purpose of this study was to evaluate predictive factors for coronary lesion and to determine the indication for preoperative coronary angiography in Korean patients with valvular heart disease (VHD). METHODS: Two hundreds eight patients (55.5 +/- 12.8 years, 99 male) with VHD underwent preoperative coronary angiography between January 1996 and January 2003 were analyzed the variables of age, gender, previous or current angina, hypertension, diabetes mellitus, smoking, dyslipidemia, obesity and familial predisposition according to the presence of coronary lesion. RESULTS: The prevalence of significant coronary artery disease in VHD patients was 26.4% (55/208). The probability of coronary lesion was higher in male above 55 years and in female above 65 years than in younger patients. The predictive factors of coronary lesion were previous or current angina (p<0.05), dyslipidemia (p<0.01), hypertension (p<0.05), previous angina (p<0.05), diabetes (p<0.01) and smoking (p<0.01) by multiple logistic regression analysis. CONCLUSION: Previous or current angina and at least one of the four risk factors (hypertension, smoking, dyslipidemia and diabetes) are predictors of coronary lesion, especially in elderly Korean patients with VHD (older than 55 years in male and 65 years in female).