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Keratinocytic Vascular Endothelial Growth Factor as a Novel Biomarker for Pathological Skin Condition
Article em En | WPRIM | ID: wpr-20366
Biblioteca responsável: WPRO
ABSTRACT
Skin is an emerging target tissue in pharmaceutical and cosmetic science. Safety assessment for dermal toxicity is a critical step for development of topically applicable pharmaceutical agents and ingredients in cosmetics. Urgent needs exist to set up toxicity testing methods for dermal safety, and identification of novel biomarkers for pathological cutaneous alteration is highly required. Here we will discuss if vascular endothelial growth factor (VEGF) has a potential as a biomarker for dermal impairment. Experimental and clinical evidences for induction of keratinocytic VEGF under pathological conditions will be reviewed.
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Texto completo: 1 Base de dados: WPRIM Assunto principal: Pele / Biomarcadores / Testes de Toxicidade / Fator A de Crescimento do Endotélio Vascular Tipo de estudo: Prognostic_studies Idioma: En Revista: Biomolecules & Therapeutics Ano de publicação: 2015 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Assunto principal: Pele / Biomarcadores / Testes de Toxicidade / Fator A de Crescimento do Endotélio Vascular Tipo de estudo: Prognostic_studies Idioma: En Revista: Biomolecules & Therapeutics Ano de publicação: 2015 Tipo de documento: Article
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