Long-Term Survival after T-cell Lymphoblastic Lymphoma Treated with One Cycle of Hyper-CVAD Regimen / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
; : 115-119, 2015.
Article
em En
| WPRIM
| ID: wpr-20369
Biblioteca responsável:
WPRO
ABSTRACT
T-lymphoblastic lymphoma (T-LBL) is a rare form of aggressive non-Hodgkin's lymphoma. The standard approach for management of T-LBL involves intensive multiagent chemotherapy regimens for induction and consolidation phases with central nervous system prophylaxis and a maintenance phase lasting 12-18 months. We report on a case of long-term survival after one cycle of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (hyper-CVAD) and high-dose methotrexate. A 30-year-old woman diagnosed with T-LBL with a large mediastinal mass underwent one cycle of hyper-CVAD. Four days after the start of treatment, the mediastinal mass was markedly reduced. Treatment continued with one cycle of consolidation chemotherapy, comprising high-dose methotrexate and high-dose cytarabine. The patient then refused all further chemotherapeutic treatment. Seven years have passed without relapse.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Recidiva
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Vincristina
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Linfoma não Hodgkin
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Indução de Remissão
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Dexametasona
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Linfócitos T
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Doxorrubicina
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Sistema Nervoso Central
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Metotrexato
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Ciclofosfamida
Limite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Cancer Research and Treatment
Ano de publicação:
2015
Tipo de documento:
Article