A Case of Reactive Plasmacytosis Mimicking Multiple Myeloma in A Patient with Primary Sjogren's Syndrome
Journal of Korean Medical Science
; : 506-508, 2005.
Article
em En
| WPRIM
| ID: wpr-204723
Biblioteca responsável:
WPRO
ABSTRACT
Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease with welldocumented association of lymphoid malignancies during the progress of the disease. Although several types of malignancy and pseudomalignancy have been reported in pSS, low-grade non-Hodgkin's lymphomas are the most frequently observed. Reactive plasmacytosis mimicking myeloma is a very rare condition in association with pSS. We describe a 72-yr-old woman with pSS who presented with hypergammaglobulinemia, and extensive bone marrow and lymph node plasmacytosis, which mimicked multiple myeloma. In this patient, there was an abnormal differentiation of memory B cells to plasma cells in the peripheral blood suggesting underlying pathogenetic mechanism for this condition.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Plasmócitos
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Exame de Medula Óssea
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Síndrome de Sjogren
/
Imunofluorescência
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Membro 7 da Superfamília de Receptores de Fatores de Necrose Tumoral
/
Antígenos CD19
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Diagnóstico Diferencial
/
Mieloma Múltiplo
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
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Female
/
Humans
Idioma:
En
Revista:
Journal of Korean Medical Science
Ano de publicação:
2005
Tipo de documento:
Article