Comparison of Doppler Ultrasonography and Hepatic Venous Pressure Gradient in Assessing Portal Hypertension in Liver Cirrhosis / 대한간학회지
The Korean Journal of Hepatology
; : 264-270, 2002.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-204920
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS:
This prospective study aimed to determine if Doppler ultrasonography can be representative of hepatic venous pressure gradient (HVPG) in assessing the severity of portal hypertension and response to drug reducing portal pressure.METHODS:
The HVPG and the parameters of Doppler ultrasonography including portal venous velocity (PVV) and splenic venous velocity, the pulsatility and resistive index of hepatic, splenic and renal arteries were measured in 105 patients with liver cirrhosis. In 31 patients the changes of hepatic venous pressure gradient and portal venous velocity after administration of terlipressin were evaluated. The patients who showed a reduction in HVPG of more than 20% of the baseline were defined as responders to terlipressin.RESULTS:
Any Doppler ultrasonographc parameters did not correlate with HVPG. Both HVPG and PVV showed a highly significant reduction after the administration of terlipressin(-28.3 +/- 3.9%, -31.2 +/- 2.2% respectively). However, PVV decreased significantly not only in responders(31.7 +/- 2.4%) but also in nonresponders(29.5 +/- 6.1%).CONCLUSION:
Doppler ultrasonography can not be representative of HVPG in assessing the severity of portal hypertension and response to drug reducing portal pressure in liver cirrhosis.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pressão Venosa
/
Velocidade do Fluxo Sanguíneo
/
Resumo em Inglês
/
Lipressina
/
Estudo Comparativo
/
Estudos Prospectivos
/
Ultrassonografia Doppler
/
Veias Hepáticas
/
Hipertensão Portal
/
Cirrose Hepática
Tipo de estudo:
Estudo observacional
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Hepatology
Ano de publicação:
2002
Tipo de documento:
Artigo