Identification and Distribution of Nontuberculous Mycobacteria from 2005 to 2011 in Cheonan, Korea / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 215-221, 2013.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-211899
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Nontuberculous mycobacteria (NTM) are considered opportunistic pathogens, and several species of NTM are associated with human diseases that typically involve the pulmonary, skin/soft tissue, or lymphatic systems; such infection may also cause disseminated diseases. Recent studies have reported increasing rates of NTM-induced disease worldwide.METHODS:
Respiratory samples are being analyzed for acid-fast bacilli (AFB) culture and NTM identification at Dankook University Hospital in Cheonan, Korea, from September 2005 to September 2011. Identification is performed by using polymerase chain reaction-restriction fragment length polymorphism analysis targeting a novel region of the rpoB gene.RESULTS:
A total of 25,133 specimens were received for AFB culture, of which 1,014 (4.0%) were NTM-positive. A total of 267 samples from 186 patients were tested for NTM identifications, and 232 samples from 157 patients were positive for NTM species. Among the patients who tested positive for NTM, 65.6% were men and the average age was 63.3 years. Mycobacterium avium complex, the most commonly detected NTM pathogen, was found in 65.9% of the 232 samples. The annual average percentage of NTM isolates from AFB culture-positive specimens was 31.3% the highest rate was seen in 2011 (44.3%), followed by 2009 (37.4%) and 2010 (37.2%). An upward trend in NTM incidence was found during the study period.CONCLUSION:
The prevalence of pulmonary NTM isolates continues to increase in Cheonan, suggesting that pulmonary NTM disease is becoming increasingly common.
Texto completo:
Disponível
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Tuberculose
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complexo Mycobacterium avium
/
Incidência
/
Prevalência
/
Distribuição por Idade
/
Coreia (Geográfico)
/
Micobactérias não Tuberculosas
Tipo de estudo:
Estudo diagnóstico
/
Estudo de incidência
/
Estudo de prevalência
/
Estudo prognóstico
Limite:
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Tuberculosis and Respiratory Diseases
Ano de publicação:
2013
Tipo de documento:
Artigo