A Case of Splenic Marginal Zone Lymphoma / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
; : 11-14, 2004.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-213942
Biblioteca responsável:
WPRO
ABSTRACT
Splenic marginal zone lymphoma (SMZL) is a rare B-cell neoplasm characterized by massive splenomegaly, moderate lymphocytosis, bone marrow intrasinusoidal involvement of lymphocytes and a relatively indolent course. We report a case of SMZL diagnosed by bone marrow studies using immunophenotyping and immunohistochemical stain, and confirmed by splenectomy. The patient was a 61-year old male, who showed mild lymphocytosis in peripheral blood and bone marrow aspirates. Immunophenotyping of bone marrow aspirates showed lymphocytes positive for CD19, CD20, CD22 (dim), CD23 (dim) and negativie for CD5 and CD10. The immunohistochemistry of bone marrow and spleen also showed lymphocytes positive for CD20 and negative at for cyclin D1. Now he is being treated for chronic obstructive pulmonary disease and will receive chemotherapy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Baço
/
Esplenectomia
/
Esplenomegalia
/
Medula Óssea
/
Imuno-Histoquímica
/
Linfócitos B
/
Linfócitos
/
Imunofenotipagem
/
Ciclina D1
/
Doença Pulmonar Obstrutiva Crônica
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo