A case of churg-strauss syndrome: evidence of eosinophilic vasculitis on liver biopsy
Allergy, Asthma & Respiratory Disease
; : 164-167, 2013.
Article
em Ko
| WPRIM
| ID: wpr-218497
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Churg-Strauss syndrome (CSS) is a rare disease characterized by pulmonary and systemic small vessel necrotizing vasculitis and peripheral blood eosinophilia occurring in asthmatics. Cases of CSS with hepatic involvement have been rarely reported. Here, we reported a case of CSS involving liver, in which liver biopsy revealed eosinophilic vasculitis.METHODS:
A 75-year-old man complained of dyspnea and hemoptysis. He had severe blood eosinophilia (white blood cell 28,320/microL, eosinophils 79%). Computed tomography of chest and abdomen showed infiltrations in lungs and multifocal infiltrations in both hepatic lobes. Methacholine PC20 was 2.89 mg/mL, which was in asthmatic range.RESULTS:
Ultrasonography-guided liver biopsy was performed, showing eosinophilic vasculitis and portal granulomas. CSS can be diagnosed based on evidence of asthma, blood eosinophilia, pulmonary infiltration and vasculitis on biopsy.CONCLUSION:
Taken together, in a suspected case of CSS presenting as hepatic involvement, liver biopsy may be useful to demonstrate the presence of vasculitis.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Eosinofilia Pulmonar
/
Asma
/
Tórax
/
Vasculite
/
Biópsia
/
Células Sanguíneas
/
Síndrome de Churg-Strauss
/
Cloreto de Metacolina
/
Doenças Raras
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Dispneia
Aspecto:
Implementation_research
Idioma:
Ko
Revista:
Allergy, Asthma & Respiratory Disease
Ano de publicação:
2013
Tipo de documento:
Article