Effect on bone formation of the autogenous tooth graft in the treatment of peri-implant vertical bone defects in the minip / 대한악안면성형재건외과학회지
Maxillofacial Plastic and Reconstructive Surgery
; : 2-2015.
Article
em En
| WPRIM
| ID: wpr-221356
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
The aim of this study was to evaluate the effect of autogenous tooth bone as a graft material for regeneration of bone in vertical bony defects of the minipigs. MATERIAL ANDMETHODS:
Six minipigs were used in this study. Four molars were extracted in the right mandibular dentition and sent to the Korea Tooth Bank for fabrication of autogenous tooth bone. Ten days later, each extraction site was implanted with MS Implant Narrow Ridge 3.0 x 10mm fixture (Osstem, Seoul, Korea) after standardized 2mm-sized artificial vertical bony defect formation. Pineappleshaped Root-On type autogenous tooth bones were applied to the vertical defects around the neck area of the posterior three fixtures and the fore-most one was not applied with autogenous bone as a control group. Each minipig was sacrificed at 4, 8, 12 weeks after fixture installation and examined radiologically and histologically. Histological evaluation was done under light microscope with Villanueva osteochrome bone staining with semi-quantitative histomorphometric study. Percentage of new bone over total area (NBF) and bone to implant contact (BIC) ratio were evaluated using digital software for area calculation.RESULT:
NBF were 48.15 +/- 18.02%, 45.50 +/- 28.37%, and 77.13 +/- 15.30% in 4, 8, and 12 weeks, respectively for experimental groups. The control group showed 37.00 +/- 11.53%, 32.25 +/- 26.99%, and 1.33 +/- 2.31% in 4,8,12 weeks, respectively. BIC ratio were 53.08 +/- 19.82%, 45.00 +/- 28.37%, and 75.13 +/- 16.55% in 4,8,12 weeks, respectively. Those for the control groups were 38.33 +/- 6.43%, 33.50 +/- 29.51 %, and 1.33 +/- 2.31% in 4, 8, 12 weeks, respectively.CONCLUSION:
Autogenous tooth bone showed higher score than control group in NBF and BIC in all the data encompassing 4,8,12 weeks specimens, but statistically significant only 12 weeks data in both NBF and BIC.
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Base de dados:
WPRIM
Assunto principal:
Osteogênese
/
Regeneração
/
Porco Miniatura
/
Dente
/
Transplantes
/
Dentição
/
Seul
/
Coreia (Geográfico)
/
Dente Molar
/
Pescoço
País/Região como assunto:
Asia
Idioma:
En
Revista:
Maxillofacial Plastic and Reconstructive Surgery
Ano de publicação:
2015
Tipo de documento:
Article