Pulmonary Cryptococcosis in Rheumatoid Arthritis Patient Treated With Leflunomide
Journal of the Korean Geriatrics Society
; : 232-236, 2014.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-226413
Biblioteca responsável:
WPRO
ABSTRACT
Leflunomide, a disease-modifying antirheumatic drug, is effective for rheumatoid arthritis as monotherapy or combination therapy with methotrexate. The most common adverse effects are diarrhea, dyspepsia, nausea, abdominal pain, oral ulcer, hepatotoxicity, skin rash, hypertension, weight loss, and interstitial lung disease. The occurrence of pulmonary cryptococcosis in leflunomide treatment has not been reported in Korea. A 74-year-old woman was admitted to hospital due to asymptomatic pulmonary nodule. She was diagnosed rheumatoid arthritis and treated with leflunomide 5 months ago due to treatment failure with methotrexate, hydroxychloroquine, and sulfasalazine. Chest radiograph and computed tomography showed solitary pulmonary nodule in her right lower lung. Pulmonary cryptococcosis was confirmed by needle biopsy of lung stained with Gomori methenamine silver and mucicarmine. The lesion was improved after antifungal therapy for 3 months.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
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Diarreia
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Doenças Negligenciadas
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artrite Reumatoide
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Sulfassalazina
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Biópsia por Agulha
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Radiografia Torácica
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Redução de Peso
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Dor Abdominal
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Metotrexato
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Falha de Tratamento
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Nódulo Pulmonar Solitário
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Doenças Pulmonares Intersticiais
Limite:
Idoso
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Coreano
Revista:
Journal of the Korean Geriatrics Society
Ano de publicação:
2014
Tipo de documento:
Artigo